Latest Publications

Information about recent research performed by FORWARD collaborators using FORWARD data.

RA Treatments Work, but Raise Infection Risk

RA Treatments Work, but Raise Infection Risk

The authors of this study, which was led by Kaleb Michaud, Ph.D., of the University of Nebraska Medical Center in Omaha, concluded that despite the efficacy of biologic DMARDs…

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Relative Impact of Pain and Fatigue

Relative Impact of Pain and Fatigue on Work Productivity in Patients with Rheumatoid Arthritis

To explore the relationship of pain and fatigue with daily activity and work productivity in rheumatoid arthritis (RA) patients from the baricitinib clinical trial, RA-BEAM.

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Safety of abatacept

Safety of abatacept compared with other biologic and conventional synthetic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis

To assess the risks of malignancies, infections and autoimmune diseases in patients with rheumatoid arthritis (RA) treated with abatacept…

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Historical Publications

Information about past research performed by FORWARD collaborators using FORWARD data, organized by year.

Shaw Y, Bradley M, Zhang C, Dominique A, Michaud K, McDonald D, Simon TA. The development of resilience among rheumatoid arthritis patients: a qualitative study. Arthritis Care & Research. 2019 Jul 8. doi: 10.1002/acr.24024. [Epub ahead of print]


Wolfe, F., Butler, S., Fitzcharles, M., et al. (2019). Revised chronic widespread pain criteria: development from and integration with fibromyalgia criteria. Scandinavian Journal of Pain. DOI:10.1515/sjpain-2019-0054. PubMed Link


Wolfe, F.,Ablin, J., Guymer, E., Littlejohn, G., Rasker, J. (2019). The relation of physical comorbidity and multimorbidity to fibromyalgia, widespread pain and fibromyalgia-related variables. The Journal of Rheumatology


Mehta B, Pedro S, Ozen G, et al. Serious infection risk in rheumatoid arthritis compared with non-inflammatory rheumatic and musculoskeletal diseases: a US national cohort study.

Ozen G, Pedro S, Wolfe F, et al. Medications associated with fracture risk in patients with rheumatoid arthritis.

Wolfe F. Fibromyalgia criteria. JPain. doi: 10.1016/j.jpain.2019.02.002. PubMed Link


Wolfe, F., Walitt, B., Rasker, J. and Häuser, W.


Wolfe, F. , Schmukler, J. , Jamal, S. , Castrejon, I. , Gibson, K. A., Srinivasan, S. , Häuser, W. and Pincus, T. (2019), Diagnosis of Fibromyalgia: Disagreement Between Fibromyalgia Criteria and Clinician‐Based Fibromyalgia Diagnosis in a University Clinic. Arthritis Care Res, 71: 343-351. doi:10.1002/acr.23731. PubMed Link


Wolfe F, Walitt B, Perrot S, Rasker JJ, Häuser W (2018) Fibromyalgia diagnosis and biased assessment: Sex, prevalence and bias. PLoS ONE, 13. doi:10.1371/journal.pone.0203755. PubMed Link


Mikuls, TR., Duryee, MJ., Rahman, R., Anderson, DR., Sayles, HR., Hollins, A., Michaud, K., Wolfe, F., Thiele, GE., Sokolove, J., Robinson, WH., Lingampalli, N., Nicholas, AP., Talmon, GA., Su, K., Zimmerman, MC., Klassen LW., Thiele, GM. Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint. Rheumatology (Oxford). 56(10):1794-1803. doi: 10.1093/rheumatology/kex212. PubMed Link


Ablin, J., Wolfe, F. A Comparative Evaluation of the 2011 and 2016 Criteria for Fibromyalgia.


Wolfe, F., Clauw, D., Fitzcharles, M., Goldenber, D., Hauser, W., Katz, R., Mease, P., Russell, A., Russell, I., Walitt, B. 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria. Seminars in Arthritis and Rheumatism46(3):319-329; doi: 10.1016/j.semarthrit.2016.08.012. PubMed Link


Wolfe, F. and Walitt, B. (2017), No Association of Fibromyalgia and Seronegative Rheumatoid Arthritis—The Need for Uniform Application of Fibromyalgia Criteria in Research Studies: Comment on the Article by Doss et al. Arthritis & Rheumatology, 69: 679-680. doi:10.1002/art.39998. PubMed Link


Ozen GPedro SHolmqvist ME, et al. Risk of diabetes mellitus associated with disease-modifying antirheumatic drugs and statins in rheumatoid arthritis.

Wolfe, F. and Walitt, B. (2016), Fibromyalgia Is Overdiagnosed in the General Population: Comment on the Article by Hootman et al. Arthritis & Rheumatology, 68: 3043-3044. doi:10.1002/art.39839. PubMed Link


Wolfe, F., Egloff, N., Hauser, W. Widespread Pain and Low Widespread Pain Index Scores among Fibromyalgia-positive Cases Assessed with the 2010/2011 Fibromyalgia Criteria.


Walitt, B., Katz, R., Bergman, M., Wolfe, F. Three-Quarters of Persons in the US Population Reporting a Clinical Diagnosis of Fibromyalgia Do Not Satisfy Fibromyalgia Criteria: The 2012 National Health Interview Survey. PLOSOne. DOI: 10.1371/journal.pone.0157235. PubMed Link



Wolfe, F. , Fitzcharles, M. , Goldenberg, D. L., Häuser, W. , Katz, R. L., Mease, P. J., Russell, A. S., Jon Russell, I. and Walitt, B. (2016), Comparison of Physician‐Based and Patient‐Based Criteria for the Diagnosis of Fibromyalgia. Arthritis Care & Research, 68: 652-659. doi:10.1002/acr.22742. PubMed Link

Walitt B, Nahin RL, Katz RS, Bergman MJ, Wolfe F (2015) The Prevalence and Characteristics of Fibromyalgia in the 2012 National Health Interview Survey. PLoS ONE. 10(9). DOI: 10.1371/journal.pone.0138024. PubMed Link


Wolfe, F. (2015) Fibromyalgia criteria in a tertiary pain clinic. Scandinavian Journal of Rheumatology, 44:5, 345-347, DOI: 10.3109/03009742.2015.1072581. PubMed Link


PubMed Link


Hauser, W., Bialas, P., Welsch, K., and Wolfe, F. Construct validity and clinical utility of current research criteria of DSM-5 somatic symptom disorder diagnosis in patients with fibromyalgia syndrome. Journal of Psychosomatic Research, 78(6) 546-552. DOI: 10.1016/j.jpsychores.2015.03.151. PubMed Link


England BR, Sayles H, Mikuls TR, Johnson DS, Michaud K. Validation of the Rheumatic Disease Comorbidity Index. Arthritis Care Res (Hoboken) 2014 Sep 3. doi: 10.1002/acr.22456. PubMed link

Wolfe F, Walitt BT, Katz RS, Häuser W. Social security work disability and its predictors in patients with fibromyalgia. Arthritis Care Res (Hoboken). 2014 Sep;66(9):1354-63. doi: 10.1002/acr.22305. PubMed link

Cannon GW, DuVall SL, Haroldsen CL, Caplan L, Curtis JR, Michaud K, et al. Persistence and Dose Escalation of Tumor Necrosis Factor Inhibitors in US Veterans with Rheumatoid Arthritis.J Rheumatol. 2014 Aug 15. pii: jrheum.140164. PubMed link

Wolfe F, Häuser W, Walitt BT, Katz RS, Rasker JJ, Russell AS. Fibromyalgia and Physical Trauma: The Concepts We Invent. J Rheumatol. 2014 Aug 1. pii: jrheum.140268. PubMed link

Oude Voshaar MA, Ten Klooster PM, Taal E, Wolfe F, Vonkeman H, Glas CA, van de Laar MA. Linking physical function outcomes in rheumatology: Performance of a crosswalk for converting HAQ scores to SF36 PF-10 scores. Arthritis Care Res (Hoboken). 2014 Apr 22. doi: 10.1002/acr.22357.PubMed link

Häuser W, Wolfe F, Henningsen P, Schmutzer G, Brähler E, Hinz A. Untying chronic pain: prevalence and societal burden of chronic pain stages in the general population – a cross-sectional survey. BMC Public Health. 2014 Apr 13;14(1):352. PubMed link

Kerr G, Aujero M, Richards J, Sayles H, Davis L, Cannon G, Caplan L, Michaud K, Mikuls T. Associations of hydroxychloroquine use with lipid profiles in rheumatoid arthritis: Pharmacologic implications. Arthritis Care Res (Hoboken). 2014 Apr 1. doi: 10.1002/acr.22341. PubMed link

Caplan L, Wolfe F, Michaud K, Quinzanos I, Hirsh JM. Health literacy is strongly associated with functional status among rheumatoid arthritis patients: A cross-sectional study. Arthritis Care and Research. 2014 Apr;66(4):508-14. doi: 10.1002/acr.22165. PubMed link

Häuser W, Brähler E, Wolfe F, Henningsen P. Patient Health Questionnaire 15 as a generic measure of severity in fibromyalgia syndrome: surveys with patients of three different settings. J Psychosom Res. 2014 Apr;76(4):307-11. doi: 10.1016/j.jpsychores.2014.01.009. PubMed link

Sokolove J, Johnson DS, Lahey LJ, Wagner CA, Cheng D, Thiele GM, Michaud K, et al. Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritis. Arthritis Rheumatol. 2014 Apr;66(4):813-21. doi: 10.1002/art.38307. PubMed link

Rasker JJ, Wolfe F. Letter to the Editor. Pain. 2014 Mar 28. pii: S0304-3959(14)00145-6. doi: 10.1016/j.pain.2014.03.016. PubMed link

Cross M, Smith E, Hoy D, Carmona L, Wolfe F, Vos T, Williams B, Gabriel S, Lassere M, Johns N, Buchbinder R, Woolf A, March L. The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study. Ann Rheum Dis. 2014 Feb 18. doi: 10.1136/annrheumdis-2013-204627. PubMed link

Wolfe F, Walitt BT, Katz RS, Häuser W. Symptoms, the nature of fibromyalgia, and diagnostic and statistical manual 5 (DSM-5) defined mental illness in patients with rheumatoid arthritis and fibromyalgia. PLoS One. 2014 14;9(2):e88740. PubMed link

Wolfe F, Walitt BT, Katz RS, Häuser W. Social security work disability and its predictors in patients with fibromyalgia. Arthritis Care Res (Hoboken). 2014 Feb 10. doi: 10.1002/acr.22305. PubMed link

Wolfe F, Michaud K, Busch RE, Katz RS, Rasker JJ, Shahouri SH, Shaver TS, Wang S, Walitt BT, Häuser W. Polysymptomatic Distress in Patients with Rheumatoid Arthritis: Understanding disproportionate response and its spectrum. Arthritis Care Res (Hoboken). 2014 Feb 4. doi: 10.1002/acr.22300. PubMed link

Wolfe F, Michaud K, Busch RE, Katz RS, Rasker JJ, Shahouri SH, Shaver TS, Wang S, Walitt BT, Häuser W. Polysymptomatic Distress in Patients with Rheumatoid Arthritis: Understanding disproportionate response and its spectrum. Arthritis Care Res (Hoboken). 2014 Feb 4. doi: 10.1002/acr.22300. PubMed link

Wolfe F. Fibromyalgia research criteria. J Rheumatol. 2014 Jan;41(1):187. doi: 10.3899/jrheum.131224. PubMed link
Michaud K, Fehringer EV, Garvin K, O’Dell JR, Mikuls TR. Rheumatoid arthritis patients are not at increased risk for 30-day cardiovascular events, infections, or mortality after total joint arthroplasty. Arthritis Res Ther. 2013;15(6):R195. PubMed link

Häuser W, Wolfe F. The Somatic Symptom Disorder in DSM 5 risks mislabelling people with major medical diseases as mentally ill. J Psychosom Res. 2013 Dec;75(6):586-7. doi: 10.1016/j.jpsychores.2013.09.005. PubMed link

Langhorst J, Hofstetter A, Wolfe F, Häuser W. Short-term stress, but not mucosal healing nor depression was predictive for the risk of relapse in patients with ulcerative colitis: a prospective 12-month follow-up study. Inflammatory Bowl Diseases. 2013:(11):2380-6 PubMed link

Wolfe F, Walitt BT, Häuser W. What is fibromyalgia, how is it diagnosed and what does it really mean? Arthritis Care and Research. 2013: doi: 10.1002 PubMed link

Hernández Alava M, Wailoo A, Wolfe F, Michaud K. A Comparison of Direct and Indirect Methods for the Estimation of Health Utilities from Clinical Outcomes. Medical Decision Making. 2013: DOI: 10.1177 PubMed link

Davis ML, Michaud K, Sayles H, Conn DL, Moreland LW, Bridges SL Jr, Mikuls TR. Associations of alcohol use with radiographic disease progression in African Americans with recent-onset rheumatoid arthritis. Journal of Rheumatology. 2013:40(9):1498-504. PubMed link

Demoruelle MK, Parish MC, Derber LA, Kolfenbach JR, Hughes-Austin JM, Weisman MH. Performance of anti-cyclic citrullinated Peptide assays differs in subjects at increased risk of rheumatoid arthritis and subjects with established disease. Arthritis Rheum. 2013 Sep;65(9):2243-52. doi: 10.1002/art.38017. PubMed link

Young KA, Deane KD, Derber LA, Hughes-Austin JM, Wagner CA, Sokolove J. Relatives without rheumatoid arthritis show reactivity to anti-citrullinated protein/peptide antibodies that are associated with arthritis-related traits: studies of the etiology of rheumatoid arthritis. Arthritis Rheum. 2013 Aug;65(8):1995-2004. doi: 10.1002/art.38022. PubMed link

Wolfe F, Walitt B. Culture, science and the changing nature of fibromyalgia. Nature Reviews Rheumatology. 2013:doi: 10.1038 PubMed link
Masri KR, Shaver T. IgG4-related systemic disease: an uncommon presentation for an uncommon disease. Rheumatol Int. 2013 Jul;33(7):1865-6. doi: 10.1007/s00296-013-2677-4. PubMed link

Oude Voshaar MA, Glas CA, ten Klooster PM, Taal E, Wolfe F, van de Laar MA. Crosscultural measurement equivalence of the Health Assessment Questionnaire II. Arthritis Care and Research. 2013:65(6):1000-4 PubMed link

Bohn D, Bernardy K, Wolfe F, Häuser W. The association among childhood maltreatment, somatic symptom intensity, depression, and somatoform dissociative symptoms in patients with fibromyalgia syndrome: a single-center cohort study. Journal of Trauma & Dissociation. 2013:14(3):342-58 PubMed link

Wolfe F, Michaud K. Reply: To PMID 22514152. Arthritis Care Res (Hoboken). 2013 May;65(5):835. doi: 10.1002/acr.21907. PubMed link

Wolfe F, Bolster MB, O’Connor CM, Michaud K, Lyles KW, Colón-Emeric CS. Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis. Journal of Bone and Mineral Research. 2013:28(5):984-91 PubMed link

Wolfe F, Brähler E, Hinz A, Häuser W. Fibromyalgia prevalence, somatic symptom reporting, and the dimensionality of polysymptomatic distress: results from a survey of the general population. Arthritis Care and Research. 2013:65(5):777-85 PubMed link

Vincent A, Lahr BD, Wolfe F, Clauw DJ, Whipple MO, Oh TH, Barton DL, St Sauver J. Prevalence of fibromyalgia: a population-based study in Olmsted County, Minnesota, utilizing the Rochester Epidemiology Project. Arthritis Care and Research. 2013:65(5):786-92 PubMed link

Hernández Alava M, Wailoo A, Wolfe F, Michaud K. The relationship between EQ-5D, HAQ and pain in patients with rheumatoid arthritis. Rheumatology. 2013: 52(5):944-50 PubMed link

Wolfe F, Walitt BT, Katz RS, Lee YC, Michaud KD, Häuser W. Longitudinal Patterns of Analgesic and Central Acting Drug Use and Associated Effectiveness in Fibromyalgia. European Journal of Pain. 2013:(4):581-6. PubMed link

Garg R, Sayles HR, Yu F, Michaud K, Singh J, Saag KG. et al. Gout-related healthcare utilization in U.S. emergency departments, 2006 through 2008. Arthritis Care and Research. 2013: 65(4):571-7 PubMed link

Chakravarty EF, Michaud K, Katz R, Wolfe F. Increased incidence of herpes zoster among patients with systemic lupus erythematosus. Lupus. 2013:(3):238-44 PubMed link

Mikuls TR, Padala PR, Sayles HR, Yu F, Michaud K, Caplan L. et al. Prospective study of posttraumatic stress disorder and disease activity outcomes in US veterans with rheumatoid arthritis. Arthritis Care and Research. 2013:Vol. 65(2):227-3 PubMed link
Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C. et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet. 2012:380(9859):2197-223 PubMed link

Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M. et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet. 2012:380(9859):2163-96 PubMed link

Wolfe F, Rasker JJ, Häuser W. Hearing loss in fibromyalgia? Somatic sensory and non-sensory symptoms in patients with fibromyalgia and other rheumatic disorders. Clin Exp Rheumatology. 2012:30(6 Suppl 74):88-93 PubMed link

Häuser W, Sarzi-Puttini P, Tölle TR, Wolfe F. Placebo and nocebo responses in randomised controlled trials of drugs applying for approval for fibromyalgia syndrome treatment: systematic review and meta-analysis. Clin Exp Rheumatology. 2012:30(6 Suppl 74):78-87 PubMed link

Wolfe F, Michaud K. Effect of body mass index on mortality and clinical status in rheumatoid arthritis. Arthritis Care and Research. 2012:Vol. 64(10):1471-9 PubMed link

Häuser W, Wolfe F. Diagnosis and diagnostic tests for fibromyalgia (syndrome). Reumatismo. 2012:64(4):194-205 PubMed link

Carter MJ, Mikuls TR, Nayak S, Fehringer EV, Michaud K. Meta-analysis: The impact of total shoulder arthroplasty on generic and shoulder-specific health-related quality of life measures. Journal of Bone and Joint Surgery. 2012:Vol.94(17)e127 1-9 PubMed link

Masri KR, Shaver TS, Shahouri SH, Wang S, Anderson JD, Busch RE. et al. Validity and reliability problems with patient global as a component of the ACR/EULAR remission criteria as used in clinical practice. Journal of Rheumatology. 2012: 39(6):1139-45 PubMed link

Anderson J, Caplan L, Yazdany J, Robbins ML, Neogi T, Michaud K. et al. Rheumatoid Arthritis Disease Activity Measures: American College of Rheumatology Recommendations for Use in Clinical Practice. Arthritis Care and Research. 2012:64(5):640-647 PubMed link

Clowse ME, Chakravarty E, Costenbader KH, Chambers C, Michaud K. The Effects of Infertility, Pregnancy Loss, and Patient Concerns on Family Size of Women with Rheumatoid Arthritis and Systemic Lupus Erythematosus. Arthritis Care and Research. 2012: Vol. 64(5):668-74 PubMed link

Mikuls TR, Levan T, Gould KA, Yu F, Thiele GM, Bynote KK, et al. Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. Arthritis Rheum. 2012 Mar;64(3):655-64. doi: 10.1002/art.33408. PubMed link

Michaud K, Vera-Llonch M, Oster G. Mortality Risk by Functional Status and Health-related Quality of Life in Patients with Rheumatoid Arthritis. J Rheumatol. 2012:39(1):54-9. PubMed link

Courvoisier DS, Agoritsas T, Glauser J, Michaud K, Wolfe F, Cantoni E, et al. Pain as an important predictor of psychosocial health in patients with rheumatoid arthritis. Arthritis Care Res (Hoboken). 2012;64(2):190-6. PubMed link
Maska L, Anderson J, Michaud K. Measures of functional status and quality of life in rheumatoid arthritis. Arthritis Care Res. 2011;63(S11):S4-S13.
Anderson JK, Zimmerman L, Caplan L, Michaud K. Measures of rheumatoid arthritis disease activity. Arthritis Care Res. 2011;63(S11):S14-S36.
Shahouri SH, Michaud K, Mikuls TR, Caplan L, Shaver TS, Anderson JD, et al. Remission of rheumatoid arthritis in clinical practice: Application of the ACR/EULAR 2011 remission criteria. Arthritis Rheum. 2011;63(11):3204-15. PMCID: 3202065. PubMed link

Smith CJ, Sayles H, Mikuls TR, Michaud K. Minocycline and doxycycline therapy in community patients with rheumatoid arthritis: prescribing patterns, patient-level determinants of use, and patient-reported side effects. Arthritis Res Ther. 2011;13(5):R168. PubMed link

Walitt B, Fitzcharles MA, Hassett AL, Katz RS, Häuser W, Wolfe F. The longitudinal outcome of fibromyalgia: a study of 1555 patients. J Rheumatol. 2011; 38(10):2238-46. PubMed link

Reid MC, Bennett DA, Chen WG, Eldadah BA, Farrar JT, Ferrell B, et al. Improving the Pharmacologic Management of Pain in Older Adults: Identifying the Research Gaps and Methods to Address Them. Pain Med. 2011;12(9):1336-57. PMCID: 3173592. PubMed link

Wolfe F, Hassett AL, Katz RS, Michaud K, Walitt B. Do we need core sets of fibromyalgia domains? The assessment of fibromyalgia (and other rheumatic disorders) in clinical practice.J Rheumatol. 2011 Jun;38(6):1104-12. doi: 10.3899/jrheum.100511. PubMed link

Wolfe F, Häuser W, Hassett AL, Katz RS, Walitt BT. The development of fibromyalgia–I: examination of rates and predictors in patients with rheumatoid arthritis (RA). Pain. 2011 Feb;152(2):291-9. doi: 10.1016/j.pain.2010.09.027. PubMed link

Wolfe F, Hassett AL, Walitt B, Michaud K. Mortality in fibromyalgia: a study of 8,186 patients over thirty-five years. Arthritis Care Res (Hoboken). 2011 Jan;63(1):94-101. doi: 10.1002/acr.20301. PubMed link

DT Felson, JS Smolen, G Wells, et al. “American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials”, Arthrit Rheum, 2011;63(3):573. PubMed link

Mikuls TR, Fay BT, Michaud K, Sayles H, Thiele GM, Caplan L, et al. Associations of disease activity and treatments with mortality in men with rheumatoid arthritis: results from the VARA registry. Rheumatology. 2011;50(1):101-9. PMCID: 3108313. PubMed link

Rasmussen A, Sevier S, Kelly JA, Glenn SB, Aberle T, Cooney CM, et al. The lupus family registry and repository. Rheumatology (Oxford). 2011 Jan;50(1):47-59. doi: 10.1093/rheumatology/keq302.PubMed link

Michaud K, Wallenstein G, Wolfe F. Treatment and nontreatment predictors of health assessment questionnaire disability progression in rheumatoid arthritis: A longitudinal study of 18,485 patients. Arthrit Care Res. 2011;63(3):366-372. PubMed link

Neumann G, Depablo P, Finckh A, Chibnik LB, Wolfe F, Duryea J. Patient repositioning reproducibility of joint space width measurements on hand radiographs. Arthritis Care Res. 2011;63:203-7. PubMed link

Wolfe F, Michaud K. The National Data Bank for Rheumatic Diseases: a Multi-Registry Rheumatic Disease Data Bank. Rheumatology. 2011;50:16-24. PubMed link
Mikuls TR1, Gould KA, Bynoté KK, Yu F, Levan TD, Thiele GM, Michaud KD. Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study. Arthritis Res Ther. 2010;12(6):R213. doi: 10.1186/ar3190. Epub 2010 Nov 18. PubMed link

Costenbader KH, Khamashta M, Ruiz-Garcia S, Perez-Rodriguez MT, Petri M, Elliott J, et al. Development and Initial Validation of the Self-Assessed Lupus Damage Index Questionnaire (LDIQ). Arthritis Care Res. 2010. PubMed link

Wolfe F, Michaud K, Li T, Katz RS. EQ-5D and SF-36 Quality of Life Measures in Systemic Lupus Erythematosus: Comparisons with RA, Non-inflammatory Rheumatic Disorders, and Fibromyalgia. J Rheumatol. 2010;37:296-304. PubMed link

Wolfe F, Clauw D, Fitzcharles MA, Goldenberg D, Katz RS, Mease P, et al. The American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity. Arthritis Care Res. 2010.

Wolfe F, Michaud K. The loss of health status in rheumatoid arthritis and the effect of biologic therapy: a longitudinal observational study. 2010. PubMed link

Wolfe F, Michaud K, Li T, Katz BS. Chronic Conditions and Health Problems in Rheumatic Diseases: Comparisons with RA, Non-inflammatory Rheumatic Disorders, Systemic Lupus Erythematosus and Fibromyalgia. J Rheumatol. 2010. PubMed link

Anderson J, Sayles H, Curtis JR, Wolfe F, Michaud K. Converting MHAQ, MDHAQ and HAQII scores into HAQ scores using models developed with a large cohort of RA patients. Arthrit Care Res. 2010;62(10):1481. PubMed link

Wolfe F. New Criteria for fibromyalgia: a twenty year journey. Arthritis Care Res. 2010. PubMed link

Wolfe F, Marmor MF. Rates and Predictors of Hydroxychloroquine Retinal Toxicity in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus Arthritis Care Res. 2010.

Wolfe F, Michaud K, Wallenstein G. Scale Characteristics and Mapping Accuracy of the US EQ-5D, UK EQ-5D, and SF-6D in Patients with Rheumatoid Arthritis. J Rheumatol. 2010;37(8):1615. PubMed link

Wolfe F, Michaud K. The Hawthorne Effect, Sponsored Trials, and the Overestimation of Treatment Effectiveness. J Rheumatol. 2010;37:2216. PubMed link
Wolfe F, Petri M, Alarcon GS, Goldman J, Chakravarty EF, Katz RS, et al. Fibromyalgia, systemic lupus erythematosus (SLE), and evaluation of SLE activity. J Rheumatol. 2009 Jan;36(1):82-8. PubMed link

Bergman MJ, Shahouri SH, Shaver TS, Anderson JD, Weidensaul DN, Busch RE, et al. Is Fatigue an Inflammatory Variable in Rheumatoid Arthritis (RA)? Analyses of Fatigue, Osteoarthritis, and Fibromyalgia. J Rheumatol. 2009;36:2788-94. PubMed link

Allaire S, Wolfe F, Niu J, LaValley MP, Zhang B, Reisine S. Current risk factors for work disability associated with rheumatoid arthritis: recent data from a US national cohort. Arthritis & Rheumatism. 2009 Mar 15;61(3):321-8.

Wolfe F. Fibromyalgia wars. J Rheumatol. 2009 Apr;36(4):671-8.

Wolfe F. Fibromyalgianess. Arthritis & Rheumatism. 2009 Jun 15;61(6):715-6.

Wolfe F, Michaud K. Out of pocket expenses and their burden in patients with rheumatoid arthritis. Arthritis & Rheumatism. 2009;61(11):1563-70.

Wolfe F, Michaud K. Outcome and predictor relationships in fibromyalgia and rheumatoid arthritis: evidence concerning the continuum versus discrete disorder hypothesis. J Rheumatol. 2009 Apr;36(4):831-6.

Wolfe F, Michaud K. Predicting depression in rheumatoid arthritis: the signal importance of pain extent and fatigue, and comorbidity. Arthritis & Rheumatism. 2009 May 15;61(5):667-73.

Wolfe F, Michaud K. Proposed metrics for the determination of rheumatoid arthritis outcome and treatment success and failure. J Rheumatol. 2009 Jan;36(1):27-33.

Wolfe F, Boers M, Felson D, Michaud K, Wells GA. Remission in rheumatoid arthritis: physician and patient perspectives. J Rheumatol. 2009 May;36(5):930-3.

Finckh A, Bansback N, Marra CA, Anis AH, Michaud K, Lubin S, White M, Sizto S, Liang MH. Treatment of very early rheumatoid arthritis with symptomatic therapy, disease-modifying antirheumatic drugs, or biologic agents: a cost-effectiveness analysis. Ann Intern Med. 2009;151(9):612. PubMed link

Pons-Estel B, Sanchez-Guerrero J, Romero-Diaz J, Inglesias A, Bonfa E, Shinjo SK, et al. Validation of the Spanish, Portuguese and French Versions of the Lupus Damage Index Questionnaire: Data from North and South America, Spain and Portugal. Lupus. 2009;18(12):1033-52.
Shaver TS, Anderson JD, Weidensaul DN, Shahouri SS, Busch RE, Mikuls TR, et al. The problem of rheumatoid arthritis disease activity and remission in clinical practice. J Rheumatol. 2008;35(6):1015-22. PubMed link

Sawitzke AD, Shi H, Finco MF, Dunlop DD, Bingham CO, 3rd, Harris CL, et al. The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial. Arthritis & Rheumatism. 2008 Oct;58(10):3183-91.

Wailoo AJ, Bansback N, Brennan A, Michaud K, Nixon RM, Wolfe F. Biologic drugs for rheumatoid arthritis in the Medicare program: a cost-effectiveness analysis. Arthritis & Rheumatism. 2008;58(4):939-46. PubMed link

Nadareishvili Z, Michaud K, Hallenbeck JM, Wolfe F. Cardiovascular, rheumatologic, and pharmacologic predictors of stroke in patients with rheumatoid arthritis: A nested, case-control study. Arthritis & Rheumatism. 2008;59(8):1090-6.

Allaire S, Wolfe F, Niu J, LaValley MP. Contemporary prevalence and incidence of work disability associated with rheumatoid arthritis in the US. Arthritis & Rheumatism. 2008;59(4):474-80.

Vera-Llonch M, Massarotti E, Wolfe F, Shadick N, Westhovens R, Sofrygin O, et al. Cost-effectiveness of abatacept in patients with moderately to severely active rheumatoid arthritis and inadequate response to methotrexate. Rheumatology (Oxford). 2008 Apr;47(4):535-41.

Vera-Llonch M, Massarotti E, Wolfe F, Shadick N, Westhovens R, Sofrygin O, et al. Cost-Effectiveness of Abatacept in Patients with Moderately to Severely Active Rheumatoid Arthritis and Inadequate Response to Tumor Necrosis Factor-alpha Antagonists. J Rheumatol. 2008.

Hoffman HM, Wolfe F, Belomestnov P, Mellis SJ. Cryopyrin-associated periodic syndromes: development of a patient-reported outcomes instrument to assess the pattern and severity of clinical disease activity. Curr Med Res Opin. 2008 Sep;24(9):2531-43.

Cannon GW, Pincus SH, Emkey RD, Denes A, Cohen SA, Wolfe F, et al. Double-blind trial of recombinant gamma-interferon versus placebo in the treatment of rheumatoid arthritis. 1989. Arthritis & Rheumatism. 2008 Feb;58(2 Suppl):S79-88.

Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II. Arthritis & Rheumatism. 2008;58(1):26-35.

Allaire S, Wolfe F, Niu J, Zhang Y, Zhang B, LaValley M. Evaluation of the effect of anti-tumor necrosis factor agent use on rheumatoid arthritis work disability: The jury is still out. Arthritis & Rheumatism. 2008;59(8):1082-9.

Simon TA, Smitten AL, Franklin J, Askling J, Lacaille D, Wolfe F, et al. Malignancies in the rheumatoid arthritis abatacept clinical development program: An epidemiological assessment. Ann Rheum Dis. 2008 Dec 3.

Wolfe F, Michaud K. Prevalence, risk, and risk factors for oral and ocular dryness with particular emphasis on rheumatoid arthritis. J Rheumatol. 2008;35(6):1023-30.

Wolfe F, Michaud K. Proposed Metrics for the Determination of Rheumatoid Arthritis Outcome and Treatment Success and Failure. J Rheumatol. 2008 Dec 1.
Aletaha D, Landewe R, Karonitsch T, Bathon J, Boers M, Bombardier C, et al. Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations. Arthritis & Rheumatism. 2008 Oct 15;59(10):1371-7.

Wolfe F, Michaud K. The challenges of determining RA disease activity and remission in clinical practice. NatClinPractRheumatol. 2008.

Wolfe F, Michaud K. The risk of myocardial infarction and pharmacologic and nonpharmacologic myocardial infarction predictors in rheumatoid arthritis: A cohort and nested case-control analysis. Arthritis & Rheumatism. 2008 Sep;58(9):2612-21.
Lee HS, Irigoyen P, Kern M, Lee A, Batliwalla F, Khalili H, et al. Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts. Arthritis & Rheumatism. 2007;56(6):1745-53. PubMed link

Wolfe F, Michaud K. Assessment of Pain in Rheumatoid Arthritis: Minimal Clinically Significant Difference, Predictors, and the Effect of Anti-Tumor Necrosis Factor Therapy. J Rheumatol. 2007.

Wolfe F, Michaud K. Biologic treatment of rheumatoid arthritis and the risk of malignancy: Analyses from a large US observational study. Arthritis & Rheumatism. 2007;56(9):2886-95.

Michaud K, Wolfe F. Comorbidities in rheumatoid arthritis. BestPractResClinRheumatol. 2007;21(5):885-906.

Caplan L, Wolfe F, Russell AS, Michaud K. Corticosteroid use in rheumatoid arthritis: prevalence, predictors, correlates, and outcomes. J Rheumatol. 2007;34(4):696-705. PubMed link

Dessein PH, Norton GR, Woodiwiss AJ, Joffe BI, Wolfe F. Influence of Nonclassical Cardiovascular Risk Factors on the Accuracy of Predicting Subclinical Atherosclerosis in Rheumatoid Arthritis. J Rheumatol. 2007;34(5):943-51.

Wolfe F, Rasker JJ, Boers M, Wells GA, Michaud K. Minimal disease activity, remission, and the long-term outcomes of rheumatoid arthritis. Arthritis & Rheumatism. 2007;57(6):935-42.

Marra CA, Marion SA, Guh DP, Najafzadeh M, Wolfe F, Esdaile JM, et al. Not all “quality-adjusted life years” are equal. J ClinEpidemiol. 2007;60(6):616-24.

Wolfe F, Michaud K. Resistance of rheumatoid arthritis patients to changing therapy: Discordance between disease activity and patients’ treatment choices. Arthritis & Rheumatism. 2007;56(7):2135-42.

Wolfe F, Caplan L, Michaud K. Rheumatoid arthritis treatment and the risk of severe interstitial lung disease. Scand J Rheumatol. 2007;36(3):172-8. PubMed link

Michaud K, Wolfe F. The development of a rheumatic disease research comorbidity index for use in outpatients patients with RA, OA, SLE and fibromyalgia (FMS). Arthritis and Rheumatism (Suppl). 2007;56(9):S596.

Benito-Garcia E, Michaud K, Wolfe F. The Effect of Low-Dose Aspirin on the Decreased Risk of Development of Dyspepsia and Gastrointestinal Ulcers Associated to Cyclooxygenase-2 Selective Inhibitors. J Rheumatol. 2007.

Wolfe F, Michaud K. The effect of methotrexate and anti-tumor necrosis factor therapy on the risk of lymphoma in rheumatoid arthritis in 19,562 patients during 89,710 PERSON-YEARS of observation. Arthritis & Rheumatism. 2007;56(5):1433-9.

Wolfe F. The effective use of questionnaires in clinical practice. Arthritis & Rheumatism. 2007;57(5):705-6.

Garcia EB, Wolfe F. The potentials and challenges of patient registries. Acta ReumatolPort. 2007;32(4):313-5.

Wolfe F, Allaire S, Michaud K. The prevalence and incidence of work disability in rheumatoid arthritis, and the effect of anti-tumor necrosis factor on work disability. J Rheumatol. 2007 Nov;34(11):2211-7.
Katz RS, Wolfe F, Michaud K. Fibromyalgia diagnosis: A comparison of clinical, survey, and American College of Rheumatology criteria. Arthritis & Rheumatism. 2006;54(1):169-76.

Clegg DO, Reda DJ, Harris CL, Klein MA, O’Dell JR, Hooper MM, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. NEnglJ Med. 2006;354(8):795-808.

Wolfe F, Michaud K. Anemia and renal function in patients with rheumatoid arthritis. J Rheumatol. 2006;33(8):1516-22.

Wolfe F, Michaud K, Simon T. Can severity be predicted by treatment variables in rheumatoid arthritis administrative data bases? J Rheumatol. 2006;33(10):1952-6.

Wolfe F, Michaud K, Strand V. Dr. Wolfe, et al reply. J Rheumatol. 2006;33(2):435.

Allaire S, Wolfe F, Niu J, Baker N, Michaud K, LaValley M. Extent of occupational hand use among persons with rheumatoid arthritis. Arthritis & Rheumatism. 2006;55(2):294-9.

Garcia EB, Michaud K, Wolfe F. Gastrointestinal prophylactic therapy among patients with arthritis treated by rheumatology specialists. J Rheumatol. 2006;33(4):779-84.

Dewitt EM, Glick HA, Albert DA, Joffe MM, Wolfe F. Medicare coverage of tumor necrosis factor alpha inhibitors as an influence on physicians’ prescribing behavior. ArchInternMed. 2006;166(1):57-63.

Finckh A, de PP, Katz JN, Neumann G, Lu Y, Wolfe F, et al. Performance of an automated computer-based scoring method to assess joint space narrowing in rheumatoid arthritis: a longitudinal study. Arthritis & Rheumatism. 2006;54(5):1444-50.

Finckh A, Choi HK, Wolfe F. Progression of radiographic joint damage in different eras. Trends towards milder disease in Rheumatoid Arthritis are attributable to improved therapy. AnnRheumDis. 2006.

Goligher EC, Duryea J, Liang MH, Wolfe F, Finckh A. Radiographic joint space width in the fingers of patients with rheumatoid arthritis of less than one year’s duration. Arthritis & Rheumatism. 2006;54(5):1440-3.

Wolfe F, Michaud K, Chakravarty EF. Rates and predictors of herpes zoster in patients with rheumatoid arthritis and non-inflammatory musculoskeletal disorders. Rheumatology (Oxford). 2006;45(11):1370-5. PubMed link

Wolfe F, Michaud K, Li T. Sleep disturbance in patients with rheumatoid arthritis: evaluation by medical outcomes study and visual analog sleep scales. J Rheumatol. 2006;33(10):1942-51.

Michaud K, Wolfe F. The association of rheumatoid arthritis and its treatment with sinus disease. J Rheumatol. 2006;33(12):2412-5.

Wolfe F, Rasker JJ. The Symptom Intensity Scale, fibromyalgia, and the meaning of fibromyalgia-like symptoms. J Rheumatol. 2006;33(11):2291-9.

Wolfe F, Caplan L, Michaud K. Treatment for rheumatoid arthritis and the risk of hospitalization for pneumonia: Associations with prednisone, disease-modifying antirheumatic drugs, and anti-tumor necrosis factor therapy. Arthritis & Rheumatism. 2006;54(2):628-34. PubMed link
Wolfe F, Katz RS, Michaud K. Jaw Pain: Its Prevalence and Meaning in Patients with Rheumatoid Arthritis, Osteoarthritis, and Fibromyalgia. J Rheumatol. 2005;32(12):2421-8.

Plenge RM, Padyukov L, Remmers EF, Purcell S, Lee AT, Karlson EW, et al. Replication of Putative Candidate-Gene Associations with Rheumatoid Arthritis in > 4,000 Samples from North America and Sweden: Association of Susceptibility with PTPN22, CTLA4, and PADI4. AmJ HumGenet. 2005;77(6):1044-60. PubMed link

Wolfe F, Michaud K. A brief introduction to the National Data Bank for Rheumatic Diseases. Clin ExpRheumatol. 2005;23(5):S168-S71.

Wolfe F, Michaud K, Pincus T. A Composite Disease Activity Scale for Clinical Practice, Observational Studies and Clinical Trials: The Patient Activity Scale (PAS/PAS-II). JRheumatol. 2005;32(12):2410-5.

Ang DC, Choi H, Kroenke K, Wolfe F. Comorbid depression is an independent risk factor for mortality in patients with rheumatoid arthritis. J Rheumatol. 2005;32(6):1013-9.

Brandt KD, Mazzuca SA, Katz BP, Lane KA, Buckwalter KA, Yocum DE, et al. Effects of doxycycline on progression of osteoarthritis: results of a randomized, placebo-controlled, double-blind trial. Arthritis & Rheumatism. 2005;52(7):2015-25.

Wolfe F, Michaud K, Strand V. Expanding the definition of clinical differences: from minimally clinically important differences to really important differences. Analyses in 8931 patients with rheumatoid arthritis. J Rheumatol. 2005;32(4):583-9.

Wolfe F, Michaud K, Choi HK, Williams R. Household income and earnings losses among 6,396 persons with rheumatoid arthritis. J Rheumatol. 2005;32(10):1875-83.

Wells GA, Boers M, Shea B, Brooks PM, Simon LS, Strand CV, et al. Minimal disease activity for rheumatoid arthritis: a preliminary definition. J Rheumatol. 2005;32(10):2016-24.

Pincus T, Wolfe F. Patient questionnaires for clinical research and improved standard patient care: is it better to have 80% of the information in 100% of patients or 100% of the information in 5% of patients? J Rheumatol. 2005;32(4):575-7.

Wolfe F, Michaud K, Pincus T. Preliminary evaluation of a visual analog function scale for use in rheumatoid arthritis. J Rheumatol. 2005;32(7):1261-6.

Pincus T, Yazici Y, Yazici H, Kavanaugh AF, Kremer JM, Wolfe F. Radiographic benefit without clinical improvement in infliximab-treated patients with rheumatoid arthritis: Comment on the article by Smolen et al. Arthritis & Rheumatism. 2005;52(12):4044-5.

Ward RJ, Chris Buckland-Wright J, Wolfe F. Relationships between tibial rim alignment and joint space width measurement reproducibility in non-fluoroscopic radiographs of osteoarthritic knees. OsteoarthritisCartilage. 2005.


Mazzuca SA, Brandt KD, Schauwecker DS, Katz BP, Meyer JM, Lane KA, et al. Severity of joint pain and kellgren-lawrence grade at baseline are better predictors of joint space narrowing than bone scintigraphy in obese women with knee osteoarthritis. J Rheumatol. 2005;32(8):1540-6.

Chakravarty EF, Michaud K, Wolfe F. Skin cancer, rheumatoid arthritis, and tumor necrosis factor inhibitors. J Rheumatol. 2005;32(11):2130-5. PubMed link

Caplan L, Russell AS, Wolfe F. Steroids for rheumatoid arthritis: the honeymoon revisited (once again). J Rheumatol. 2005;32(10):1863-5. PubMed link

Wolfe F, Michaud K, Pincus T, Furst D, Keystone E. The disease activity score is not suitable as the sole criterion for initiation and evaluation of anti-tumor necrosis factor therapy in the clinic: discordance between assessment measures and limitations in questionnaire use for regulatory purposes. Arthritis & Rheumatism. 2005;52(12):3873-9.

Lee AT, Li W, Liew A, Bombardier C, Weisman M, Massarotti EM, et al. The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status. Genes Immun. 2005;6(2):129-33.

Wolfe F, Michaud K. Towards an epidemiology of rheumatoid arthritis outcome with respect to treatment: randomized controlled trials overestimate treatment response and effectiveness. Rheumatology (Oxford). 2005;44 Suppl 4:iv18-iv22.

Wolfe F, Michaud K, Pincus T, Pangan AL, Kent j. Usefulness Of A Visual Analog Function Scale In Ra Clinical Trials: Increased Sensitivity Compared With Conventional Measures. ArthritisRheum. 2005;50.

Wolfe F. Why the HAQ-II can be an effective substitute for the HAQ. ClinExpRheumatol. 2005;23(5 Suppl 39):S29-S30.

Allaire S, Wolfe F, Niu J, LaValley M, Michaud K. Work disability and its economic effect on 55-64-year-old adults with rheumatoid arthritis. Arthritis & Rheumatism. 2005;53(4):603-8.

Walker N, Michaud K, Wolfe F. Work limitations among working persons with rheumatoid arthritis: results, reliability, and validity of the work limitations questionnaire in 836 patients. J Rheumatol. 2005;32(6):1006-12.
Wolfe F. A short history of data banking in the United States from 1974 to 2003. JRheumatolSuppl. 2004;69:41-5.

Wolfe F, Zhao S, Pettitt D. Blood Pressure Destabilization and Edema Among 8538 Users of Celecoxib, Rofecoxib, and Nonselective Nonsteroidal Antiinflammatory Drugs (NSAID) and Nonusers of NSAID Receiving Ordinary Clinical Care. JRheumatol. 2004;31(6):1143-51.

Fewell z, Hernan MA, Wolfe F, Tilling H, Choi HK, Sterne AC. Controlling for time-dependent confounding using marginal structural models. Stata Journal. 2004;4(4):402-20.

Wolfe F, Michaud K. Corticosteroids increase the risk of diabetes mellitus in RA and contribute to the risk of myocardial infarction and heart failure. AnnRheumDis. 2004;63:379.

Wolfe F, Michaud K. Data collection, maintenance, and analysis for rheumatic disease research. RheumDisClinNorth Am. 2004;30(4):753-68.

Robinson RL, Birnbaum HG, Morley MA, Sisitsky T, Greenberg PE, Wolfe F. Depression and fibromyalgia: treatment and cost when diagnosed separately or concurrently. J Rheumatol. 2004;31(8):1621-9.

Wolfe F, Michaud K, Pincus T. Development and validation of the health assessment questionnaire II: a revised version of the health assessment questionnaire. Arthritis & Rheumatism. 2004;50(10):3296-305.

Wolfe F, Michaud K, Pincus T. Do rheumatology cost-effectiveness analyses make sense? Rheumatology(Oxford). 2004;43(1):4-6.

Wolfe F. Fatigue assessments in rheumatoid arthritis: comparative performance of visual analog scales and longer fatigue questionnaires in 7760 patients. JRheumatol. 2004;31(10):1896-902.

Wolfe F. From the outside of Plato’s cave. Rheumatology(Oxford). 2004;43(1):112-3.

Wolfe F, Michaud K. Heart failure in rheumatoid arthritis: rates, predictors, and the effect of anti-tumor necrosis factor therapy. AmJMed. 2004;116(5):305-11.

Stern R, Wolfe F. Infliximab dose and clinical status: results of 2 studies in 1642 patients with rheumatoid arthritis. JRheumatol. 2004;31(8):1538-45.

Wolfe F, Michaud K, Burke TA, Zhao SZ. Longer use of COX-2-specific inhibitors compared to nonspecific nonsteroidal antiinflammatory drugs: a longitudinal study of 3639 patients in community practice. JRheumatol. 2004;31(2):355-8.

Wolfe F, Michaud K. Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients. Arthritis & Rheumatism. 2004;50(6):1740-51.

Wolfe F, Caplan L, Michaud K. Measuring the efficacy and effectiveness of rheumatoid arthritis therapy: time to change our thinking and adopt a new model. JRheumatol. 2004;31(12):2317-9. PubMed link

Pincus T, Koch G, Lei H, Mangal B, Sokka T, Moskowitz R, et al. Patient Preference for Placebo, Acetaminophen (paracetamol) or Celecoxib Efficacy Studies (PACES): two randomised, double blind, placebo controlled, crossover clinical trials in patients with knee or hip osteoarthritis. AnnRheumDis. 2004;63(8):931-9.

Wolfe F, Michaud K. Prednisone but not biologics or DMARDs is associated with increased risk of myocardial infarction in persons with RA. AnnRheumDis. 2004;63:69.

Wolfe F, Michaud K. Rates and risk factors for herpes zoster in patients with rheumatoid arthritis. AnnRheumDis. 2004;63:103.

Wolfe F. Rheumatology grand rounds at rush: patient self-report data are key to better patient care. J ClinRheumatol. 2004;10(6):347-9.

Wolfe F, Michaud K. Severe rheumatoid arthritis (RA), worse outcomes, comorbid illness, and sociodemographic disadvantage characterize RA patients with fibromyalgia. JRheumatol. 2004;31(4):695-700.

Mazzuca SA, Brandt KD, Katz BP, Lane KA, Bradley JD, Heck LW, et al. Subject retention and adherence in a randomized placebo-controlled trial of a disease-modifying osteoarthritis drug. Arthritis & Rheumatism. 2004;51(6):933-40.

Wolfe F, Michaud K, Kahler K, Omar M. The Short Arthritis Assessment Scale: a brief assessment questionnaire for rapid evaluation of arthritis severity in research and clinical practice. JRheumatol. 2004;31(12):2472-9.


Wolfe F, Michaud K, Anderson J, Urbansky K. Tuberculosis infection in patients with rheumatoid arthritis and the effect of infliximab therapy. Arthritis & Rheumatism. 2004;50(2):372-9.

Sharp JT, Wolfe F, Lassere M, Boers M, van der HD, Larsen A, et al. Variability of precision in scoring radiographic abnormalities in rheumatoid arthritis by experienced readers. JRheumatol. 2004;31(6):1062-72.

Wolfe F, Michaud K, Dewitt EM. Why results of clinical trials and observational studies of antitumour necrosis factor (anti-TNF) therapy differ: methodological and interpretive issues. AnnRheumDis. 2004;63 Suppl 2:ii13-ii7.
Pincus T, Strand V, Koch G, Amara I, Crawford B, Wolfe F, et al. An index of the three core data set patient questionnaire measures distinguishes efficacy of active treatment from that of placebo as effectively as the American College of Rheumatology 20% response criteria (ACR20) or the Disease Activity Score (DAS) in a rheumatoid arthritis clinical trial. Arthritis & Rheumatism. 2003;48(3):625-30.

Wolfe F, Michaud K, Choi HK, Williams R. Annual and lifetime productivity costs and income losses in Persons with Rheumatoid Arthritis. Arthritis and Rheumatism (Suppl). 2003;48:S243.

Michaud K, Messer J, Choi HK, Wolfe F. Direct medical costs and their predictors in patients with rheumatoid arthritis: a three-year study of 7,527 patients. Arthritis & Rheumatism. 2003 Oct;48(10):2750-62.

Wolfe F, Burke TA, Pettitt D. Do gastroprotective drugs prevent NSAID toxicity? Reply. JRheumatol. 2003;30(1):203-.

Wolfe F, Freundlich B, Straus WL. Increase in cardiovascular and cerebrovascular disease prevalence in rheumatoid arthritis. JRheumatol. 2003;30(1):36-40.

Wolfe F. Pain extent and diagnosis: development and validation of the regional pain scale in 12,799 patients with rheumatic disease. JRheumatol. 2003;30(2):369-78.

Wolfe F, Michaud K, Gefeller O, Choi HK. Predicting mortality in patients with rheumatoid arthritis. Arthritis & Rheumatism. 2003;48(6):1530-42.

Wolfe F, Fries JF. Rate of death due to leukemia/lymphoma in patients with rheumatoid arthritis. Arthritis & Rheumatism. 2003;48(9):2694-5.

Wolfe F. Stop using the American College of Rheumatology criteria in the clinic. JRheumatol. 2003;30(8):1671-2.

Wolfe F, Pincus T, Thompson AK, Doyle J. The assessment of rheumatoid arthritis and the acceptability of self-report questionnaires in clinical practice. Arthritis & Rheumatism. 2003;49(1):59-63.

Wolfe F, Michaud K, Stephenson B, Doyle J. Toward a Definition and Method of Assessment of Treatment Failure and Treatment Effectiveness: The Case of Leflunomide versus Methotrexate. JRheumatol. 2003;30(8):1725-32.
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, Plant BJ, et al. A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes Immun. 2002;3(3):170-6.

Pincus T, Ferraccioli G, Sokka T, Larsen A, Rau R, Kushner I, et al. Evidence from clinical trials and long-term observational studies that disease-modifying anti-rheumatic drugs slow radiographic progression in rheumatoid arthritis: updating a 1983 review. Rheumatology(Oxford). 2002;41(12):1346-56.

Wolfe F, Anderson J, Burke TA, Arguelles LM, Pettitt D. Gastroprotective therapy and risk of gastrointestinal ulcers: risk reduction by COX-2 therapy. JRheumatol. 2002;29(3):467-73.

Wolfe F, Pincus T, Tennant A. HAQ-II: Application of modern item response theory to the design of an improved HAQ questionnaire. AnnRheumDis. 2002;61:190.

Fries JF, Wolfe F, Apple R, Erlich H, Bugawan T, Holmes T, et al. HLA-DRB1 genotype associations in 793 white patients from a rheumatoid arthritis inception cohort: frequency, severity, and treatment bias. Arthritis & Rheumatism. 2002;46(9):2320-9.

Wolfe F. Hypertension among patients with rheumatoid and osteoarthritis participating in the National Data Bank for Rheumatic Diseases. JRheumatol. 2002.
Wolfe F, Flowers N, Burke TA, Arguelles LM, Pettitt D. Increase in lifetime adverse drug reactions, service utilization, and disease severity among patients who will start COX-2 specific inhibitors: quantitative assessment of channeling bias and confounding by indication in 6689 patients with rheumatoid arthritis and osteoarthritis. JRheumatol. 2002;29(5):1015-22.

Choi HK, Hernan MA, Seeger JD, Robins JM, Wolfe F. Methotrexate therapy and mortality in patients with rheumatoid arthritis: a prospective study. Lancet. 2002;359:1173-7.

Hurst S, Kallan MJ, Wolfe FJ, Fries JF, Albert DA. Methotrexate, hydroxychloroquine, and intramuscular gold in rheumatoid arthritis: relative area under the curve effectiveness and sequence effects. JRheumatol. 2002;29(8):1639-45.

Duryea J, Zaim S, Wolfe F. Neural network based automated algorithm to identify joint locations on hand/wrist radiographs for arthritis assessments. MedPhys. 2002;29(3):403-11.

Wolfe F, Lane NE, Buckland-Wright C. Radiographic Methods in Knee Osteoarthritis: A Further Comparison of Semiflexed (MTP), Schuss-Tunnel, and Weight-Bearing Anteroposterior Views for Joint Space Narrowing and Osteophytes. JRheumatol. 2002;29(12):2597-601.

Wolfe F. The determination and measurement of functional disability in rheumatoid arthritis. Arthritis Res. 2002;4 Suppl 2:S11-S5.

Ethgen O, Kahler KH, Kong SX, Reginster JY, Wolfe F. The effect of health related quality of life on reported use of health care resources in patients with osteoarthritis and rheumatoid arthritis: a longitudinal analysis. JRheumatol. 2002;29(6):1147-55.

Wolfe F, Lane NE. The longterm outcome of osteoarthritis: rates and predictors of joint space narrowing in symptomatic patients with knee osteoarthritis. JRheumatol. 2002;29(1):139-46.

Wolfe F. The psychometrics of functional status questionnaires: room for improvement. JRheumatol. 2002;29(5):865-8.

Wolfe F, Michaud K. Toward an acceptable definition of DMARD failure and abnormal health status in RA. Arthritis and Rheumatism (Suppl). 2002;46(9):S865.

Choi HK, Michaud K, Wolfe F. Utility measures in rheumatic diseases. Arthritis and Rheumatism (Suppl). 2002;46(9).
Wolfe F, Cush JJ, O’Dell JR, Kavanaugh A, Kremer JM, Lane NE, et al. Consensus recommendations for the assessment and treatment of rheumatoid arthritis1330. JRheumatol. 2001;28(6):1423-30.

Pincus T, Koch GG, Sokka T, Lefkowith J, Wolfe F, Jordan JM, et al. A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee1214. Arthritis & Rheumatism. 2001;44(7):1587-98.

Wolfe F, Choi HK. Benchmarking and the percentile assessment of RA: adding a new dimension to rheumatic disease measurement. AnnRheumDis. 2001;60(11):994-5.

Wolfe CV. Disability evaluation of fibromyalgia. Phys Med Rehabil Clin N Am. 2001 Aug;12(3):709-18.

Wolfe F, O’Dell JR, Kavanaugh A, Wilske K, Pincus T. Evaluating severity and status in rheumatoid arthritis1328. JRheumatol. 2001;28(6):1453-62.

Wolfe F, Pincus T, O’Dell J. Evaluation and documentation of rheumatoid arthritis disease status in the clinic: which variables best predict change in therapy. JRheumatol. 2001;28(7):1712-7.

Pincus T, Wolfe F, Strand V, Kavanaugh A, Crawford B, Felson D. Patient questionnaire data discriminate between drug versus placebo as effectively as the ACR20 in a clinical trial of patients with rheumatoid arthritis (RA). Arthritis and Rheumatism (Suppl). 2001;43(9):S288.

Pincus T, Sokka T, Wolfe F. Premature mortality in patients with rheumatoid arthritis: evolving concepts. Arthritis & Rheumatism. 2001;44(6):1234-6.

Wolfe F, Strand V. Radiography of rheumatoid arthritis in the time of increasing drug effectiveness795. CurrRheumatolRep. 2001;3(1):46-52.

Wolfe F, Rehman Q, Lane NE, Kremer J. Starting a disease modifying antirheumatic drug or a biologic agent in rheumatoid arthritis: standards of practice for RA treatment1143. JRheumatol. 2001;28(7):1704-11.

Wolfe F, Pincus T. The level of inflammation in rheumatoid arthritis is determined early and remains stable over the longterm course of the illness. JRheumatol. 2001;28(8):1817-24.

Wolfe F, Flowers N, Anderson J, Urbansky K. Tuberculosis rates are not increased in rheumatoid arthritis (RA). Arthritis and Rheumatism (Suppl). 2001;44(9):S105-S-.

Wolfe F, Pincus T, Fries JF. Usefulness of the HAQ in the clinic. AnnRheumDis. 2001;60(8):811.

Wolfe F. Which HAQ is best? A comparison of the HAQ, MHAQ and RA-HAQ, a difficult 8 item HAQ (DHAQ), and a rescored 20 item HAQ (HAQ20): analyses in 2,491 rheumatoid arthritis patients following leflunomide initiation. JRheumatol. 2001;28(5):982-9.
Wolfe F. A reappraisal of HAQ disability in rheumatoid arthritis. Arthritis & Rheumatism. 2000;43(12):2751-61.

Pincus T, Wolfe F. An infrastructure of patient questionnaires at each rheumatology visit: improving efficiency and documenting care. J Rheumatol. 2000;27(12):2727-30.

Wolfe F, van der Heijde DM, Larsen A. Assessing radiographic status of rheumatoid arthritis: introduction of a short erosion scale. JRheumatol. 2000;27(9):2090-9.

Wolfe F. For example is not evidence: fibromyalgia and the law. J Rheumatol. 2000 May;27(5):1115-6.

Wolfe F, Kong SX, Watson DJ. Gastrointestinal symptoms and health related quality of life in patients with arthritis. JRheumatol. 2000;27(6):1373-8.

Wolfe F. Management of fibromyalgia. Ann Intern Med. 2000 Jun 20;132(12):1004; author reply 5.

Wolfe F, Skevington SM. Measuring the epidemiology of distress: The rheumatology distress index. JRheumatol. 2000;27(8):2000-9.

Albert DA, Aksentijevich S, Hurst S, Fries JF, Wolfe F. Modeling therapeutic strategies in rheumatoid arthritis: Use of decision analysis and Markov models. JRheumatol. 2000;27(3):644-52.

Wolfe F, Zhao S, Lane N. Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. Arthritis & Rheumatism. 2000;43(2):378-85.

Wolfe F. Sayin’ “stand and deliver, for you are a bold deceiver”: Faking Fibromyalgia. JRheumatol. 2000;27(11):2534-5. PubMed link

Hawley DJ, Wolfe F, Lue FA, Moldofsky H. Seasonal symptom severity in patients with rheumatic diseases: a study of 1,424 patients. J Rheumatol. 2001 Aug;28(8):1900-9.

Wolfe F, Hawley DJ, Goldenberg DL, Russell IJ, Buskila D, Neumann L. The assessment of functional impairment in fibromyalgia (FM): Rasch analyses of 5 functional scales and the development of the FM Health Assessment Questionnaire. JRheumatol. 2000;27(8):1989-99.

Wolfe F, Hawley DJ. The comparative risk and predictors of adverse gastrointestinal events in rheumatoid arthritis and osteoarthritis: A prospective 13 year study of 2131 patients. JRheumatol. 2000;27(7):1668-73.

Wolfe F. The effect of smoking on clinical, laboratory, and radiographic status in rheumatoid arthritis [see comments]. JRheumatol. 2000;27(3):630-7.

Wolfe F. The importance of gastrointestinal (GI) symptom severity in rheumatoid and osteoarthritis: symptom rates and risk for GI hospitalization. J Rheumatol. 2000;27(7):1661-7.

Wolfe F, Pincus T. The rheumatoid arthritis percentile activity score (PAS): methods and validation. Arthritis and Rheumatism (Suppl). 2000;43(9):S151.
Wolfe F. “Silicone Related Symptoms” Are Common In Patients with Fibromyalgia:No Evidence for A New Disease. JRheumatol. 1999;26(5):1172-5.

Aronoff GM, Markowitz M, Dorto AJ, Ranavaya MI, Talmage JB, Wolfe F, et al. AADEP Position Paper – Fibromyalgia: impairment and disability issues. American Academy of Disability Examining Physicians. 1999;8(3 – Special Pull out section):1-10.

Wolfe F. Critical issues in longitudinal and observational studies: Purpose, short versus long term, selection of study instruments, methods, outcomes, and biases. JRheumatol. 1999;26(2):469-72.

Wolfe F, Pincus T. Current comment – Listening to the patient – A practical guide to self-report questionnaires in clinical care. Arthritis & Rheumatism. 1999;42(9):1797-808.

Wolfe F. Determinants of WOMAC function, pain and stiffness scores: evidence for the role of low back pain, symptom counts, fatigue and depression in osteoarthritis, rheumatoid arthritis and fibromyalgia. Rheumatology (Oxford). 1999;38(4):355-61.

Wolfe F, Hawley DJ, Pincus T. Disease modifying antirheumatic drugs (DMARD) and DMARD combination use by 3604 patients of 303 US rheumatologists. Arthritis and Rheumatism (Suppl). 1999;42:S379.

Ehrich EW, Schnitzer TJ, McIlwain H, Levy R, Wolfe F, Weisman M, et al. Effect of specific COX-2 inhibition in osteoarthritis of the knee: a 6 week double blind, placebo controlled pilot study of rofecoxib. Rofecoxib Osteoarthritis Pilot Study Group491. JRheumatol. 1999;26(11):2438-47.

Wolfe F, Hawley DJ. Evidence of disordered symptom appraisal in fibromyalgia: increased rates of reported comorbidity and comorbidity severity. Clin Exp Rheumatol. 1999 May-Jun;17(3):297-303.

Wolfe MM, Lichtenstein DR, Singh G. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs [see comments] [published erratum appears in N Engl J Med 1999 Aug 12;341(7):548]. New England Journal of Medicine. 1999;340(24):1888-99.

Wolfe F, Hawley DJ, Anderson JA. Inflammation as measured by the esr predicts cardiovascular mortality across all rheumatic disorders: a 25-year prospective study 0f 5,822 patients. Arthritis and Rheumatism (Suppl). 1999;42(9):S299.

Wolfe EW, Chiu CW. Measuring change across multiple occasions using the Rasch Rating Scale Model. J OutcomeMeas. 1999;3(4):360-81.

Wolfe EW, Chiu CW. Measuring pretest-posttest change with a Rasch Rating Scale Model. J OutcomeMeas. 1999;3(2):134-61.

Kavanaugh AF, Wolfe F, Ward M. New treatments for rheumatoid arthritis: A managed care perspective – Questions and answer session. AmJ ManagCare. 1999;5(14):S866-S9.

Wolfe F, Lassere M, van der HD, Stucki G, Suarez-Almazor M, Pincus T, et al. Preliminary core set of domains and reporting requirements for longitudinal observational studies in rheumatology45. JRheumatol. 1999;26(2):484-9.

Wolfe F. Psychological distress and rheumatic disease39. ScandJRheumatol. 1999;28(3):131-6.

Smolen JS, Strand V, Cardiel M, Edworthy S, Furst D, Gladman D, et al. Randomized clinical trials and longitudinal observational studies in systemic lupus erythematosus: Consensus on a preliminary core set of outcome domains. JRheumatol. 1999;26(2):504-7.

Wolfe F, Kong SX. Rasch analysis of the Western Ontario MacMaster questionnaire (WOMAC) in 2205 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. Ann Rheum Dis. 1999;58(9):563-8.

Kavanaugh AF, Wolfe F, Auslander M, Bresloff T, Clark DL, Hillman D, et al. Roundtable II: Cost concerns for rheumatoid arthritis treatment. AmJ ManagCare. 1999;5(14):S880-S8.

Wolfe F, Anderson J. Silicone filled breast implants and the risk of fibromyalgia and rheumatoid arthritis. JRheumatol. 1999;26(9):2025-8.

Wolfe F, Hawley DJ, Pincus T. Standard values for self-report questionnaires: assessments in 20,574 rheumatic disease patients. Arthritis and Rheumatism (Suppl). 1999;42:S75-S.

Buckland-Wright JC, Wolfe F, Ward RJ, Flowers N, Hayne C. Substantial superiority of semiflexed (MTP) views in knee osteoarthritis: A comparative radiographic study, without fluoroscopy, of standing extended, semiflexed (MTP), and schuss views. JRheumatol. 1999;26(12):2664-74.

Wolfe F. The burden of rheumatoid arthritis. AmJ ManagCare. 1999;5(14):S852-S9.

Pincus T, Swearingen C, Wolfe F. Toward a multidimensional Health Assessment Questionnaire (MDHAQ): assessment of advanced activities of daily living and psychological status in the patient-friendly health assessment questionnaire format. Arthritis & Rheumatism. 1999 Oct;42(10):2220-30.

Hawley DJ, Wolfe F, Pincus T. Use of combination therapy in the routine care of patients with rheumatoid arthritis: Physician and patient surveys. ClinExpRheumatol. 1999;17(6):S78-S82.

Flowers N, Wolfe F. What do rheumatologists do in their practices? Arthritis and Rheumatism (Suppl). 1999;41(9):S337.

Maini RN, Wolfe F. Workshop summary: health outcomes and health economic issues surrounding the use of biological therapies in patients with rheumatoid arthritis. Rheumatology(Oxford). 1999;38 Suppl 2:48-9.
Wolfe F. A comparison of IgM rheumatoid factor by nephelometry and latex methods: Clinical and laboratory significance. ArthritCare Res. 1998;11(2):89-93.

Wolfe F, Albert DA, Pincus T. A survey of United States rheumatologists concerning effectiveness of disease-modifying antirheumatic drugs and prednisone in the treatment of rheumatoid arthritis. ArthritCare Res. 1998;11(5):375-81.

Wolfe F, Neumann L, Buskila D. Altered nociception, but not fibromyalgia, after cervical spine injury: Comment on the article by Buskila et al – Reply. Arthritis & Rheumatism. 1998 -32676;41(1):183-4.

Lawrence RC, Helmick CG, Arnett FC, Deyo RA, Felson DT, Giannini EH, et al. Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis & Rheumatism. 1998;41(5):778-99.

Wolfe F, Winfield JB. Fibromyalgia Consensus Report: A few more comments. JcrJ ClinRheumatol. 1998;4(3):118-9.

Wolfe F. Fibromyalgia in a grand bio-psycho-social model – Reply. JRheumatol. 1998;25(5):1029-30.

Wolfe F. Inflammatory activity, but not methotrexate or prednisone use predicts non_Hodgkin’s lymphoma in rheumatoid arthritis. Arthritis and Rheumatism (Suppl). 1998;41:S188.

Wolfe F, Hawley DJ, Pincus T. Methotrexate alters the course of rheumatoid arthritis (RA). Increased survival of methotrexate treated RA patients: a 25-years study of 1,842 patients. Arthritis & Rheumatism. 1998;41(9):S188.

Wolfe F, Hawley DJ. Psychosocial factors and the fibromyalgia syndrome. ZRheumatol. 1998;57:88-91.

Wolfe F, Sharp JT. Radiographic outcome of recent-onset rheumatoid arthritis: A 19-year study of radiographic progression. Arthritis & Rheumatism. 1998;41(9):1571-82.

Wolfe FA. The causes of fibromyalgia. JcrJ ClinRheumatol. 1998;4(6):299-300.

Wolfe F, Zwillich SH. The long-term outcomes of rheumatoid arthritis: A 23-year prospective, longitudinal study of total joint replacement and its predictors in 1,600 patients with rheumatoid arthritis. Arthritis & Rheumatism. 1998;41(6):1072-82.

Wolfe F, Hawley DJ. The long-term outcomes of rheumatoid arthritis: Work disability: a prospective 18 year study of 823 patients. JRheumatol. 1998;25(11):2108-17.


Wolfe F, Flowers N, Anderson J. The National Rheumatic Disease Data Bank: case mix and severity characteristics of patients in rheumatological practice. Arthritis and Rheumatism (Suppl). 1998;41(9):S132.


Wolfe F. What use are fibromyalgia control points? Dr. Wolfe replies. JRheumatol. 1998;25(12):2476.


Wolfe F. What use are fibromyalgia control points? JRheumatol. 1998;25(3):546-50.

Prupas HM1, Loose LD, Spindler JS, Dietz AJ Jr, Gum OB, Weisman MH,et al. Tenidap in patients with rheumatoid arthritis. A 4-week, placebo-controlled study. Scand J Rheumatol. 1996;25(6):345-51. PubMed link